Aspirin given shortly after a heart attack decreases the risk of death. Hazardous to health regulations coshh 2002 as amended. California, new jersey, florida, pennsylvania, minnesota, massachusetts. State righttoknow regulations component massachusettsnew jersey pennsylvania illinois rhode island acetylsalicylic acid aspirin x x x u. Keep container tightly closed do not eat, drink or smoke when using this product wash skin thoroughly after handling.
Bioaccumulation accumulationno information available. This product contains the following ingredients for which the state of california has found to cause reproductive harm male which would require a warning under the statute. Other information prepared by regulatory affairs thermo fisher scientific email. Aspirin, also known as acetylsalicylic acid asa, is a medication used to reduce pain, fever, or inflammation. Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Slightly hazardous in case of skin contact corrosive. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910.
Rat 340 mgkgoacetylsalicylic acid skin corrosionirritation skin rabbitoacetylsalicylic acid result. Acetylsalicylic acid aspirin 50782 developmental female reproductive developmental u. Safety data sheet northwest missouri state university. Strong oxidizing agents, strong reducing agents, bases, alcohols, metal. Department of transportation reportable quantity rq. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. Precautionary statements p261 avoid breathing dust. This product contains acetylsalicylic acid, a chemical known. Page 6 of 8 msds acetic acid photo chemically produced hydroxyl radicals. Sulfuric acid, acs safety data sheet according to federal register vol. Safety data sheet according to 29cfr19101200 and ghs rev. Acetylsalicylic acid aspirin can be found on the following state right to know lists. First aid measures description of first aid measures. First aid measures always seek professional medical attention after first aid measures are provided.
O acetylsalicylic acid 2acetoxybenzoic acid aspirin formula. In the us, acetylsalicylic acid is a member of the following drug classes. The information in cameo chemicals comes from a variety of data sources. Synthesis of acetylsalicylic acid essay free essays, term.
See actual entry in rtecs for complete information. Bioaccumulation no information available chemical name log pow acetylsalicylic acid aspirin 50782 1. Aspirin material safety data sheet cas no 50782 sdsmsds. Our msds database is an easy to use, do it yourself tool, and best of all. One reagent lane fair lawn, nj 07410 for information in north america, call. Aspirin is only found in individuals who have consumed this drug. It is also soluble in ethanol at 50 mgml and will dissolve in solutions of alkali hydroxides and carbonates with decomposition. Acetic acid, glacial alcohol of vinegar carboxylic acid c2 ethanoic acid ethylic acid methanecarboxylic acid pyroligneous acid vinegar acid 1. Novacyl safety data sheet for rhodine 3020, version 11, 20 february 2014. This study is aimed at determining the solubility of acetylsalicylic acid in ethanol, acetone, propylene glycol, and 2propanol, in addition to comparing their solubility values with the expected from an ideal solution. As one of the most regularly tradedin medicines in the world, acetylsalicylic acid has been scarcely researched when in solution. Acetylsalicylic acid an overview sciencedirect topics. Material safety data sheet page 1 of 2 acetylsalicylic acid. Acetylsalicylic acid is prepared by reacting acetic anhydride with salicylic acid at a temperature of acetic acid or aromatic, acyclic, or chlorinated hydrocarbons or by the addition of catalysts such as acids or tertiary amines.
Acetylsalicylic acid not listed as a carcinogen by acgih, iarc, ntp, or ca prop 65. When released into air, this material is expected to have a halflife between 10 and 30 days. No skin irritation serious eye damageeye irritation eyes rabbitoacetylsalicylic. Contact a licensed professional waste disposal service to dispose of this material. Not all of the mass of an aspirin tablet is acetylsalicylic acid, as there are starch binders added to hold the tablet together. Hazardous decomposition products formed under fire conditions. Ignition sources, contact with water, excess heat, exposure to moist air or water. This product contains acetylsalicylic acid aspirin, a. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy.
Other references state that a 10 g dose 143 mgkg may be fatal in humans. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The following statements isare made in order to comply with the california safe drinking water act. Material safety data sheet acetylsalicylic acid product observe all federal, state, and local environmental regulations. Ac158180000, ac158180500, ac158185000, ac385760000 synonyms. Nov 14, 2007 as one of the most regularly tradedin medicines in the world, acetylsalicylic acid has been scarcely researched when in solution. The following statements isare made in order to comply with.
Acetylsalicylic acid is slightly soluble in water, with a limit of solubility reported as approximately 3 mgml at 25 deg c. Aspirin is an orally administered nonsteroidal antiinflammatory agent. Acetylsalicylic acid 50782 100 toxicological data on ingredients. Hazardous in case of skin contact irritant, of eye contact irritant. This agent exhibits analgesic, antipyretic, and anticoagulant properties. Acetylsalicylic acid aspirin 50782 ec50 360 mgl 1 h ec50 900 mgl 1 h 48h ec50. Aspirin or acetylsalicylic acid acetosal is a drug in the family of salicylates, often used as an analgesic against minor pains and aches, antipyretic against fever, and antiinflammatory. Sigmaaldrich offers a number of acetylsalicylic acid products. Most important symptoms and effects, both acute and delayed. N dot marine pollutant n dot severe marine pollutant n. Safety data sheet chandlergilbert community college. Acetylsalicylic acid aspirin not listed not listed ec50 360 mgl 1 h ec50 900 mgl 1 h ec50.
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. This study is aimed at determining the solubility of acetylsalicylic acid in ethanol, acetone, propylene glycol, and 2propanol, in addition to comparing their solubility values with the expected. Product and company identification acetylsalicylic acid. The balanced chemical reaction of the formation of aspirin. Synthesis of acetylsalicylic acid topics, sample papers. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. This product contains the following ingredients for which the state of. Apr 12, 2020 acetylsalicylic acid asa is better known to most people by its common name, aspirin. Excerpt from erg guide 154 substances toxic andor corrosive noncombustible.
It results from the elimination of a molecule of water from two molecules of acetic acid see fig. National library of medicine hazardous substances data bank online. Solubility of acetylsalicylic acid in ethanol, acetone. Will likely be mobile in the environment due to its water solubility. Ecotrin aspirin dose, indications, adverse effects. Pdr drug summaries are concise pointofcare prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice pdr s drug summaries are available free of charge and serve as a great resource for us based mds, dos, nps and pas in patient practice.
This material is considered hazardous by the osha hazard communication standard 29 cfr 1910. Physical and chemical properties molecular formula c9h8o4. The balanced chemical reaction of the formation of. Oral, category 4 skin corrosionirritation, category 3. Identification of the substancemixture and of the companyundertaking 1. Material safety data sheet anokaramsey community college. A combination of sodium salicylate and acetyl chloride, this medication is the first nonsteroidal antiinflammatory drug to be developed, and its been in use for over a century. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Seek medical attention if irritation, discomfort, or vomiting persists. Specific inflammatory conditions which aspirin is used to treat include kawasaki disease, pericarditis, and rheumatic fever. Acetylsalicylic acid get uptodate information on acetylsalicylic acid side effects, uses, dosage, overdose, pregnancy, alcohol and more. Aqueous solutions of acetylsalicylic acid are most stable at ph 2 3, but to assure full.
This chemical is considered hazardous according to the 2012 osha hazard communication. Oacetylsalicylic acid 2acetoxybenzoic acid aspirin formula. In some countries, this medicine may only be approved for veterinary use. Hazards identification potential acute health effects. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters 150 feet for liquids and at least 25 meters 75 feet for solids. Slightly hazardous in case of skin contact corrosive, permeator, of ingestion, of. As the reaction proceeds, the solid salicylic acid disappears and the acetylsalicylic acid product. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation.
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